Gene
rassf1
- ID
- ZDB-GENE-040912-14
- Name
- Ras association domain family member 1
- Symbol
- rassf1 Nomenclature History
- Previous Names
-
- wu:fc17f02
- zgc:112224
- zgc:92505
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Predicted to have metal ion binding activity. Predicted to be involved in intracellular signal transduction and regulation of microtubule cytoskeleton organization. Human ortholog(s) of this gene implicated in breast cancer; reproductive organ cancer (multiple); transitional cell carcinoma; and urinary system cancer (multiple). Is expressed in several structures, including immature eye; intermediate cell mass of mesoderm; nervous system; pharyngeal arch; and ventral mesoderm. Orthologous to human RASSF1 (Ras association domain family member 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 12 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:92505 (16 images)
- IMAGE:6912198 (11 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000159 | Ras-associating domain |
| Domain | IPR001368 | TNFR/NGFR cysteine-rich region |
| Domain | IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain |
| Domain | IPR011524 | SARAH domain |
| Domain | IPR033600 | Ras association domain-containing protein 1, RA domain |
| Family | IPR033614 | Ras association domain-containing protein 1-6 |
| Homologous_superfamily | IPR029071 | Ubiquitin-like domain superfamily |
| Homologous_superfamily | IPR046349 | C1-like domain superfamily |
Domain Details Per Protein
| Protein | Length | C1-like domain superfamily | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | Ras-associating domain | Ras association domain-containing protein 1-6 | Ras association domain-containing protein 1, RA domain | SARAH domain | TNFR/NGFR cysteine-rich region | Ubiquitin-like domain superfamily |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q66HV2
|
363 | ||||||||
|
UniProtKB:A0A8M2BL97
|
340 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
rassf1-201
(1)
|
Ensembl | 1,597 nt | ||
| mRNA |
rassf1-202
(1)
|
Ensembl | 2,159 nt | ||
| mRNA |
rassf1-203
(1)
|
Ensembl | 1,432 nt |
Interactions and Pathways
No data available
Plasmids
No data available