Gene
snrnp70
- ID
- ZDB-GENE-040825-2
- Name
- small nuclear ribonucleoprotein 70 (U1)
- Symbol
- snrnp70 Nomenclature History
- Previous Names
-
- snrp70
- U1 small ribonucleoprotein 70kd (1)
- wu:fc20b04
- zgc:136450
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to have U1 snRNA binding activity and mRNA binding activity. Involved in hematopoietic stem cell differentiation. Predicted to localize to U1 snRNP and U2-type prespliceosome. Human ortholog(s) of this gene implicated in disease of mental health and systemic lupus erythematosus. Is expressed in central nervous system; hematopoietic stem cell; and motor neurons. Orthologous to human SNRNP70 (small nuclear ribonucleoprotein U1 subunit 70).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7147833 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR000504 | RNA recognition motif domain |
Domain | IPR022023 | U1 small nuclear ribonucleoprotein of 70kDa N-terminal |
Domain | IPR034143 | snRNP70, RNA recognition motif |
Family | IPR051183 | U1 snRNP 70 kDa and U11/U12 snRNP 35 kDa |
Homologous_superfamily | IPR012677 | Nucleotide-binding alpha-beta plait domain superfamily |
Homologous_superfamily | IPR035979 | RNA-binding domain superfamily |
Domain Details Per Protein
Protein | Length | Nucleotide-binding alpha-beta plait domain superfamily | RNA-binding domain superfamily | RNA recognition motif domain | snRNP70, RNA recognition motif | U1 small nuclear ribonucleoprotein of 70kDa N-terminal | U1 snRNP 70 kDa and U11/U12 snRNP 35 kDa |
---|---|---|---|---|---|---|---|
UniProtKB:Q6DRE8
|
495 | ||||||
UniProtKB:E7EY23
|
162 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
mRNA |
snrnp70-201
(1)
|
Havana | 2488 nt | |
mRNA |
snrnp70-202
(1)
|
Havana | 885 nt |
Interactions and Pathways
No data available
Plasmids
No data available