Gene
her11
- ID
- ZDB-GENE-040824-4
- Name
- hairy-related 11
- Symbol
- her11 Nomenclature History
- Previous Names
-
- him (1)
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Exhibits protein heterodimerization activity. Involved in midbrain-hindbrain boundary development and negative regulation of neurogenesis. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in spondylocostal dysostosis. Is expressed in several structures, including heart; liver; margin; midbrain hindbrain boundary; and midbrain hindbrain boundary neural plate. Orthologous to human HES7 (hes family bHLH transcription factor 7).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Hairy and Enhancer of Split/HEY-related | Helix-loop-helix DNA-binding domain superfamily | Myc-type, basic helix-loop-helix (bHLH) domain |
|---|---|---|---|---|
|
UniProtKB:Q6W4T8
|
274 |
Interactions and Pathways
No data available
Plasmids
No data available