Gene
prpf3
- ID
- ZDB-GENE-040823-3
- Name
- PRP3 pre-mRNA processing factor 3 homolog (yeast)
- Symbol
- prpf3 Nomenclature History
- Previous Names
-
- HPRP3
- wu:fa11f05
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Involved in retina development in camera-type eye. Predicted to localize to U4/U6 x U5 tri-snRNP complex. Human ortholog(s) of this gene implicated in retinitis pigmentosa and retinitis pigmentosa 18. Orthologous to human PRPF3 (pre-mRNA processing factor 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7138399 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| retinitis pigmentosa 18 | Alliance | Retinitis pigmentosa 18 | 601414 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Pre-mRNA-splicing factor 3 domain | PWI domain | PWI domain superfamily | Small nuclear ribonucleoprotein Prp3, C-terminal domain | U4/U6 small nuclear ribonucleoprotein Prp3 |
|---|---|---|---|---|---|---|
|
UniProtKB:A4QP06
|
699 |
Interactions and Pathways
No data available
Plasmids
No data available