Gene
epb41l3a
- ID
- ZDB-GENE-040822-8
- Name
- erythrocyte membrane protein band 4.1-like 3a
- Symbol
- epb41l3a Nomenclature History
- Previous Names
-
- zgc:92004
- zmp:0000000522 (1)
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Predicted to enable actin binding activity and structural molecule activity. Acts upstream of or within regulation of excitatory synapse assembly. Predicted to be located in cell-cell junction; cytoskeleton; and plasma membrane. Is expressed in nervous system; optic cup; and trigeminal placode. Human ortholog(s) of this gene implicated in esophagus squamous cell carcinoma. Orthologous to human EPB41L3 (erythrocyte membrane protein band 4.1 like 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7152107 (10 images)
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Fierro et al., 2018
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| sa14659 | Allele with one point mutation | Unknown | Splice Site | ENU | |
| sa37970 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa44205 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa44206 | Allele with one point mutation | Unknown | Premature Stop | ENU |
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Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Band 4.1, C-terminal | Band 4.1 domain | Band 4.1-like protein 3, FERM domain, F1 sub-domain | Ezrin/radixin/moesin-like | FERM/acyl-CoA-binding protein superfamily | FERM adjacent | FERM central domain | FERM conserved site | FERM, C-terminal PH-like domain | FERM domain | FERM, N-terminal | FERM superfamily, second domain | PH-like domain superfamily | SAB domain | Ubiquitin-like domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PFY0
|
1073 | |||||||||||||||
|
UniProtKB:A0A8M9P5U6
|
1088 | |||||||||||||||
|
UniProtKB:Q68EI5
|
826 | |||||||||||||||
|
UniProtKB:A0A8M9PLP9
|
1053 | |||||||||||||||
|
UniProtKB:A0A8M9P5V2
|
903 |
1 - 5 of 10 Show all
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
epb41l3a-201
(1)
|
Ensembl | 3,052 nt | ||
| mRNA |
epb41l3a-202
(1)
|
Ensembl | 3,344 nt |
1 - 2 of 2
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance