Gene

cpa2

ID
ZDB-GENE-040801-182
Name
carboxypeptidase A2 (pancreatic)
Symbol
cpa2 Nomenclature History
Previous Names
  • zgc:92530
Type
protein_coding_gene
Location
Chr: 25 Mapping Details/Browsers
Description
Predicted to enable metallocarboxypeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in endocrine system and pancreas. Orthologous to human CPA2 (carboxypeptidase A2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
20 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa24634Allele with one point mutationUnknownSplice SiteENU
sa30224Allele with one point mutationUnknownSplice SiteENU
sa44261Allele with one point mutationUnknownSplice SiteENU
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Sequence Targeting Reagents
No data available
Human Disease
Associated With cpa2 Human Ortholog
No data available
Associated With cpa2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000834 Peptidase M14, carboxypeptidase A
Domain IPR003146 Carboxypeptidase, activation peptide
Domain IPR034248 Carboxypeptidase A, carboxypeptidase domain
Homologous_superfamily IPR036990 Metallocarboxypeptidase-like, propeptide
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Domain Details Per Protein
Protein Length Carboxypeptidase A, carboxypeptidase domain Carboxypeptidase, activation peptide Metallocarboxypeptidase-like, propeptide Peptidase M14, carboxypeptidase A
UniProtKB:Q6DHB8 424
UniProtKB:F1QVD7 422
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 25
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA cpa2-201 (1) Ensembl 1,341 nt
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH211-266K8ZFIN Curated Data
EncodesESTfb63e06Rauch et al., 2003
EncodescDNAMGC:92530ZFIN Curated Data
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanCPA27
Amino acid sequence comparison (1)
Conserved genome location (synteny) (2)
MouseCpa26
Amino acid sequence comparison (1)
Conserved genome location (synteny) (2)
Citations
1 - 6 of 6
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