Gene
ptger2b
- ID
- ZDB-GENE-040724-267
- Name
- prostaglandin E receptor 2b (subtype EP2)
- Symbol
- ptger2b Nomenclature History
- Previous Names
-
- PRS3 (1)
- si:ch211-13n20.1
- si:dkey-29m11.3
- zgc:136608
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Exhibits prostaglandin E receptor activity. Predicted to be involved in several processes, including adenylate cyclase-activating G protein-coupled receptor signaling pathway; cellular response to prostaglandin E stimulus; and positive regulation of cytosolic calcium ion concentration. Predicted to localize to plasma membrane. Human ortholog(s) of this gene implicated in asthma, nasal polyps, and aspirin intolerance. Is expressed in several structures, including eye; gill; heart; liver; and pleuroperitoneal region. Orthologous to human PTGER2 (prostaglandin E receptor 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Tsuge et al., 2013
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| asthma, nasal polyps, and aspirin intolerance | Alliance | {Asthma, aspirin-induced, susceptibility to} | 208550 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like | Prostacyclin (prostanoid IP) receptor | Prostanoid receptor |
|---|---|---|---|---|---|
|
UniProtKB:Q5RI92
|
341 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ptger2b-201
(1)
|
Ensembl | 2,330 nt |
Interactions and Pathways
No data available
Plasmids
No data available