Gene

tgfa

ID

ZDB-GENE-040724-208

Name

transforming growth factor, alpha

Symbol

tgfa Nomenclature History

Previous Names

si:ch211-10e8.7

Type

protein_coding_gene

Location

Chr: 6 Mapping Details/Browsers

Description

Predicted to have epidermal growth factor receptor binding activity and growth factor activity. Predicted to be involved in epidermal growth factor receptor signaling pathway and positive regulation of cell population proliferation. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in gastroenteritis and pancreatic cancer. Is expressed in midbrain; retina; and third ventricle. Orthologous to human TGFA (transforming growth factor alpha).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

5 figures from 5 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With tgfa Human Ortholog

No data available

Associated With tgfa Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000742	EGF-like domain

Domain Details Per Protein

Protein	Length	EGF-like domain
UniProtKB:A0A8M3B0K7 InterPro	222
UniProtKB:A0A8M3BAH4 InterPro	207
UniProtKB:Q7T011 InterPro	191
UniProtKB:A0A8M3ATI5 InterPro	210
UniProtKB:A0A8M2BDJ4 InterPro	203