Gene
arg1
- ID
- ZDB-GENE-040724-181
- Name
- arginase 1
- Symbol
- arg1 Nomenclature History
- Previous Names
-
- si:ch211-146f4.3 (1)
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to have arginase activity and manganese ion binding activity. Predicted to be involved in arginine catabolic process to ornithine. Predicted to localize to cytosol. Human ortholog(s) of this gene implicated in asthma; hepatocellular carcinoma; and hyperargininemia. Is expressed in eye. Orthologous to human ARG1 (arginase 1).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 4 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
hyperargininemia | Alliance | Argininemia | 207800 |
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | Arginase | Ureohydrolase | Ureohydrolase domain superfamily | Ureohydrolase, manganese-binding site |
---|---|---|---|---|---|
UniProtKB:E7F8R4
|
341 |
Interactions and Pathways
No data available
Plasmids
No data available