Gene

arg1

ID
ZDB-GENE-040724-181
Name
arginase 1
Symbol
arg1 Nomenclature History
Previous Names
  • si:ch211-146f4.3 (1)
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Predicted to have arginase activity and manganese ion binding activity. Predicted to be involved in arginine catabolic process to ornithine. Predicted to localize to cytosol. Human ortholog(s) of this gene implicated in asthma; hepatocellular carcinoma; and hyperargininemia. Is expressed in eye. Orthologous to human ARG1 (arginase 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With arg1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
hyperargininemia Alliance Argininemia 207800
Associated With arg1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Binding_site IPR020855 Ureohydrolase, manganese-binding site
Family IPR006035 Ureohydrolase
Family IPR014033 Arginase
Homologous_superfamily IPR023696 Ureohydrolase domain superfamily
Domain Details Per Protein
Protein Length Arginase Ureohydrolase Ureohydrolase domain superfamily Ureohydrolase, manganese-binding site
UniProtKB:E7F8R4 341
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA arg1-201 (1) Ensembl 1,041 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations