Gene
ift140
- ID
- ZDB-GENE-040724-165
- Name
- intraflagellar transport 140 homolog (Chlamydomonas)
- Symbol
- ift140 Nomenclature History
- Previous Names
-
- si:ch211-153c20.3 (1)
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Predicted to be involved in intraciliary retrograde transport. Predicted to localize to axoneme; ciliary basal body; and intraciliary transport particle A. Human ortholog(s) of this gene implicated in retinitis pigmentosa and short-rib thoracic dysplasia 9 with or without polydactyly. Orthologous to human IFT140 (intraflagellar transport 140).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Helm et al., 2017
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| short-rib thoracic dysplasia 9 with or without polydactyly | Alliance | Short-rib thoracic dysplasia 9 with or without polydactyly | 266920 |
| Retinitis pigmentosa 80 | 617781 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR024336 | tRNA-splicing endonuclease, subunit Sen54, N-terminal |
| Homologous_superfamily | IPR011990 | Tetratricopeptide-like helical domain superfamily |
| Homologous_superfamily | IPR015943 | WD40/YVTN repeat-like-containing domain superfamily |
| Homologous_superfamily | IPR036322 | WD40-repeat-containing domain superfamily |
| Repeat | IPR001680 | WD40 repeat |
Domain Details Per Protein
| Protein | Length | Tetratricopeptide-like helical domain superfamily | tRNA-splicing endonuclease, subunit Sen54, N-terminal | WD40 repeat | WD40-repeat-containing domain superfamily | WD40/YVTN repeat-like-containing domain superfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9Q896
|
1446 | |||||
|
UniProtKB:A0A8M9PXA0
|
1458 | |||||
|
UniProtKB:F1QG20
|
1445 | |||||
|
UniProtKB:A0A8M3ANT2
|
1457 | |||||
|
UniProtKB:A0A8M9Q5D1
|
669 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| aberrant processed transcript |
ift140-202
(1)
|
Ensembl | 741 nt | ||
| mRNA |
ift140-201
(1)
|
Ensembl | 4,885 nt | ||
| mRNA |
ift140-203
(1)
|
Ensembl | 4,338 nt |
Interactions and Pathways
No data available
Plasmids
No data available