Gene

nelfe

ID

ZDB-GENE-040718-69

Name

negative elongation factor complex member E

Symbol

nelfe Nomenclature History

Previous Names

rdbp
zgc:92496

Type

protein_coding_gene

Location

Chr: 19 Mapping Details/Browsers

Description

Predicted to have RNA binding activity. Involved in positive regulation of hematopoietic stem cell differentiation. Predicted to localize to NELF complex. Orthologous to human NELFE (negative elongation factor complex member E).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:92496 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 2 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With nelfe Human Ortholog

No data available

Associated With nelfe Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000504	RNA recognition motif domain
Domain	IPR034637	Negative elongation factor E, RNA recognition motif
Family	IPR033102	Negative elongation factor E
Homologous_superfamily	IPR012677	Nucleotide-binding alpha-beta plait domain superfamily
Homologous_superfamily	IPR035979	RNA-binding domain superfamily

Domain Details Per Protein

Protein	Length	Negative elongation factor E	Negative elongation factor E, RNA recognition motif	Nucleotide-binding alpha-beta plait domain superfamily	RNA-binding domain superfamily	RNA recognition motif domain
UniProtKB:A0A8M9PN91 InterPro	378
UniProtKB:Q1LWQ2 InterPro	346
UniProtKB:Q6DHD7 InterPro	346

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
aberrant processed transcript	nelfe-202 (1) Ensembl	Ensembl	322 nt	Select Tool
mRNA	nelfe-201 (1) Ensembl	Ensembl	1,202 nt	Select Tool
mRNA	nelfe-203 (1) Ensembl	Ensembl	1,638 nt	Select Tool
mRNA	nelfe-204 (1) Ensembl	Ensembl	779 nt	Select Tool
mRNA	nelfe-205 (1) Ensembl	Ensembl	3,119 nt	Select Tool ZFIN BLAST
mRNA	nelfe-206 (1) Ensembl	Ensembl	2,928 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations