Gene

zgc:92360

ID

ZDB-GENE-040718-470

Name

zgc:92360

Symbol

zgc:92360 Nomenclature History

Previous Names

adap1 (1)

Type

protein_coding_gene

Location

Chr: 6 Mapping Details/Browsers

Description

Predicted to have GTPase activator activity; metal ion binding activity; and phosphatidylinositol bisphosphate binding activity. Predicted to be involved in positive regulation of GTPase activity. Predicted to localize to intracellular membrane-bounded organelle and plasma membrane. Is expressed in digestive system; epidermis; periderm; and pharyngeal arch. Orthologous to human ADAP1 (ArfGAP with dual PH domains 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

7 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:92360 (13 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Melvin et al., 2013
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With zgc:92360 Human Ortholog

No data available

Associated With zgc:92360 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001164	Arf GTPase activating protein
Domain	IPR001849	Pleckstrin homology domain
Domain	IPR037849	ADAP, PH domain 1
Domain	IPR037851	ADAP, PH domain 2
Family	IPR052589	Arf-GAP with dual PH domain-containing protein
Homologous_superfamily	IPR011993	PH-like domain superfamily
Homologous_superfamily	IPR037278	ARFGAP/RecO-like zinc finger
Homologous_superfamily	IPR038508	ArfGAP domain superfamily