Gene
thop1
- ID
- ZDB-GENE-040718-47
- Name
- thimet oligopeptidase 1
- Symbol
- thop1 Nomenclature History
- Previous Names
-
- fb74b01
- wu:fb74b01
- zgc:92139 (1)
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to have metalloendopeptidase activity. Predicted to be involved in peptide metabolic process and proteolysis. Predicted to localize to mitochondrial intermembrane space. Is expressed in lens. Orthologous to human THOP1 (thimet oligopeptidase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7137009 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001567 | Peptidase M3A/M3B catalytic domain |
| Family | IPR045090 | Peptidase M3A/M3B |
| Homologous_superfamily | IPR024077 | Neurolysin/Thimet oligopeptidase, domain 2 |
| Homologous_superfamily | IPR024079 | Metallopeptidase, catalytic domain superfamily |
| Homologous_superfamily | IPR024080 | Neurolysin/Thimet oligopeptidase, N-terminal |
Domain Details Per Protein
| Protein | Length | Metallopeptidase, catalytic domain superfamily | Neurolysin/Thimet oligopeptidase, domain 2 | Neurolysin/Thimet oligopeptidase, N-terminal | Peptidase M3A/M3B | Peptidase M3A/M3B catalytic domain |
|---|---|---|---|---|---|---|
|
UniProtKB:E7EZ90
|
707 | |||||
|
UniProtKB:Q6DHR6
|
686 |
Interactions and Pathways
No data available
Plasmids
No data available