Gene
lygl1
- ID
- ZDB-GENE-040718-461
- Name
- lysozyme g-like 1
- Symbol
- lygl1 Nomenclature History
- Previous Names
-
- LysG (1)
- zgc:92608
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to enable lysozyme activity. Predicted to be involved in defense response to Gram-positive bacterium. Predicted to act upstream of or within cell wall macromolecule catabolic process and peptidoglycan catabolic process. Predicted to be active in extracellular region. Is expressed in macrophage. Orthologous to several human genes including LYG2 (lysozyme g2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:92608 (8 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Glycoside hydrolase, family 23 | Lysozyme-like domain superfamily |
|---|---|---|---|
|
UniProtKB:A0A8M2BKV1
|
185 | ||
|
UniProtKB:Q6DH80
|
196 |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-42H24 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:92608 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001002706 (1) | 821 nt | ||
| Genomic | GenBank:CR774199 (1) | 162722 nt | ||
| Polypeptide | UniProtKB:Q6DH80 (1) | 196 aa |
No data available
- Luckner, B., Essfeld, F., Ayobahan, S.U., Richling, E., Eilebrecht, E., Eilebrecht, S. (2023) Transcriptomic profiling of TLR-7-mediated immune-challenge in zebrafish embryos in the presence and absence of glucocorticoid-induced immunosuppression. Ecotoxicology and environmental safety. 266:115570115570
- Chen, H., Chen, X., Song, T.Y., Ge, J.Q. (2022) Expression Profiles of Zebrafish (Danio rerio) Lysozymes and Preparation of c-Type Lysozyme with High Bacteriolytic Activity against Vibrio vulnificus. Antibiotics (Basel, Switzerland). 11(12):
- Mu, X., Qi, S., Wang, H., Yuan, L., Wang, C., Li, Y., Qiu, J. (2022) Bisphenol analogues induced metabolic effects through eliciting intestinal cell heterogeneous response. Environment International. 165:107287
- Metikala, S., Casie Chetty, S., Sumanas, S. (2021) Single-cell transcriptome analysis of the zebrafish embryonic trunk. PLoS One. 16:e0254024
- Xie, Y., Tolmeijer, S., Oskam, J.M., Tonkens, T., Meijer, A.H., Schaaf, M.J.M. (2019) Glucocorticoids inhibit macrophage differentiation towards a pro-inflammatory phenotype upon wounding without affecting their migration. Disease models & mechanisms. 12(5):
- Bayés, À., Collins, M.O., Reig-Viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J.S., Emes, R.D., Grant, S.G. (2017) Evolution of complexity in the zebrafish synapse proteome. Nature communications. 8:14613
- Emerson, S.E., St Clair, R.M., Waldron, A.L., Bruno, S.R., Duong, A., Driscoll, H.E., Ballif, B.A., McFarlane, S., Ebert, A.M. (2017) Identification of target genes downstream of Semaphorin6A/PlexinA2 signaling in zebrafish. Developmental Dynamics : an official publication of the American Association of Anatomists. 246(7):539-549
- Liu, Q.N., Xin, Z.Z., Zhang, D.Z., Jiang, S.H., Chai, X.Y., Li, C.F., Zhou, C.L., Tang, B.P. (2016) Molecular identification and expression analysis of a goose-type lysozyme (LysG) gene in yellow catfish Pelteobagrus fulvidraco. Fish & shellfish immunology. 58:423-428
- Oksanen, K.E., Myllymäki, H., Ahava, M.J., Mäkinen, L., Parikka, M., Rämet, M. (2016) DNA Vaccination Boosts Bacillus Calmette-Guérin Protection against Mycobacterial Infection in Zebrafish. Developmental and comparative immunology. 54(1):89-96
- Wu, C.C., Kruse, F., Vasudevarao, M.D., Junker, J.P., Zebrowski, D.C., Fischer, K., Noël, E.S., Grün, D., Berezikov, E., Engel, F.B., van Oudenaarden, A., Weidinger, G., Bakkers, J. (2016) Spatially Resolved Genome-wide Transcriptional Profiling Identifies BMP Signaling as Essential Regulator of Zebrafish Cardiomyocyte Regeneration. Developmental Cell. 36(1):36-49
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