Gene
rspo1
- ID
- ZDB-GENE-040718-44
- Name
- R-spondin 1
- Symbol
- rspo1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to have heparin binding activity. Involved in angiogenesis; hematopoietic stem cell differentiation; and vascular endothelial growth factor receptor signaling pathway. Localizes to Golgi apparatus and cytosol. Is expressed in several structures, including nervous system; regenerating fin; reproductive system; steroid hormone secreting cell; and tail bud. Orthologous to human RSPO1 (R-spondin 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 15 figures from 9 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb1071 (6 images)
Wild Type Expression Summary
- All Phenotype Data
- 16 figures from 3 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR043601 | R-spondin, Fu-CRD domain |
| Family | IPR051514 | R-spondin domain-containing protein |
| Homologous_superfamily | IPR009030 | Growth factor receptor cysteine-rich domain superfamily |
| Homologous_superfamily | IPR036383 | Thrombospondin type-1 (TSP1) repeat superfamily |
| Repeat | IPR000884 | Thrombospondin type-1 (TSP1) repeat |
| Repeat | IPR006212 | Furin-like repeat |
Domain Details Per Protein
| Protein | Length | Furin-like repeat | Growth factor receptor cysteine-rich domain superfamily | R-spondin domain-containing protein | R-spondin, Fu-CRD domain | Thrombospondin type-1 (TSP1) repeat | Thrombospondin type-1 (TSP1) repeat superfamily |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q6DHR0
|
261 | ||||||
|
UniProtKB:M5AP50
|
261 |
Interactions and Pathways
No data available
Plasmids
No data available