Gene
sesn1
- ID
- ZDB-GENE-040718-408
- Name
- sestrin 1
- Symbol
- sesn1 Nomenclature History
- Previous Names
-
- si:ch211-51a19.4
- WITHDRAWN: zgc:103669
- zgc:103669 (1)
- zgc:91970
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to have leucine binding activity and oxidoreductase activity, acting on peroxide as acceptor. Involved in determination of left/right symmetry. Predicted to colocalize with GATOR2 complex; TORC2 complex; and cytoplasm. Is expressed in several structures, including anterior axial hypoblast; central nervous system; mesoderm; presumptive paraxial mesoderm; and pronephros. Orthologous to human SESN1 (sestrin 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 14 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:103669 (18 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | AhpD-like | Sestrin |
|---|---|---|---|
|
UniProtKB:U3JAG5
|
547 | ||
|
UniProtKB:Q6DG05
|
488 | ||
|
UniProtKB:Q5RGN4
|
499 | ||
|
UniProtKB:A0A8M2B7J7
|
558 |
Interactions and Pathways
No data available
Plasmids
No data available