Gene

gsto1

ID

ZDB-GENE-040718-365

Name

glutathione S-transferase omega 1

Symbol

gsto1 Nomenclature History

Previous Names

fd58h04
wu:fd58h04
zgc:92254

Type

protein_coding_gene

Location

Chr: 13 Mapping Details/Browsers

Description

Predicted to have glutathione dehydrogenase (ascorbate) activity. Predicted to be involved in oxidation-reduction process. Predicted to localize to cytoplasm. Human ortholog(s) of this gene implicated in Alzheimer's disease and Parkinson's disease. Is expressed in brain; gill; liver; and pleuroperitoneal region. Orthologous to human GSTO1 (glutathione S-transferase omega 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

5 figures from 4 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With gsto1 Human Ortholog

No data available

Associated With gsto1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR004045	Glutathione S-transferase, N-terminal
Domain	IPR004046	Glutathione S-transferase, C-terminal
Domain	IPR010987	Glutathione S-transferase, C-terminal-like
Family	IPR005442	Glutathione S-transferase, omega-class
Family	IPR040079	Glutathione transferase family
Family	IPR045073	Glutathione S-transferase Omega/Tau-like
Family	IPR050983	Glutathione S-transferase Omega/HSP26
Homologous_superfamily	IPR036249	Thioredoxin-like superfamily
Homologous_superfamily	IPR036282	Glutathione S-transferase, C-terminal domain superfamily