Gene
hax1
- ID
- ZDB-GENE-040718-26
- Name
- HCLS1 associated protein X-1
- Symbol
- hax1 Nomenclature History
- Previous Names
-
- zgc:92196
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to be involved in negative regulation of apoptotic process. Human ortholog(s) of this gene implicated in severe congenital neutropenia. Is expressed in several structures, including hatching gland; lens; mesoderm; myotome; and solid lens vesicle. Orthologous to human HAX1 (HCLS1 associated protein X-1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7158282 (17 images)
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Doll et al., 2020
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| severe congenital neutropenia 3 | Alliance | Neutropenia, severe congenital 3, autosomal recessive | 610738 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR017248 | HS1-associating protein X-1 |
Domain Details Per Protein
| Protein | Length | HS1-associating protein X-1 |
|---|---|---|
|
UniProtKB:Q6DHN8
|
286 |
Interactions and Pathways
No data available
Plasmids
No data available