Gene
kpna2
- ID
- ZDB-GENE-040718-22
- Name
- karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
- Symbol
- kpna2 Nomenclature History
- Previous Names
-
- hm:zeh0389
- hm:zeh0389r
- zeh0389
- zeh0389r
- zgc:113902
- zgc:86945 (1)
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to have nuclear localization sequence binding activity. Predicted to be involved in NLS-bearing protein import into nucleus. Predicted to localize to cytosol; nuclear pore; and nucleoplasm. Is expressed in proliferative region. Orthologous to human KPNA2 (karyopherin subunit alpha 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7147301 (14 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR002652 | Importin-alpha, importin-beta-binding domain |
| Family | IPR024931 | Importin subunit alpha |
| Homologous_superfamily | IPR011989 | Armadillo-like helical |
| Homologous_superfamily | IPR016024 | Armadillo-type fold |
| Homologous_superfamily | IPR036975 | Importin-alpha, importin-beta-binding domain superfamily |
| Repeat | IPR000225 | Armadillo |
| Repeat | IPR032413 | Atypical Arm repeat |
Domain Details Per Protein
| Protein | Length | Armadillo | Armadillo-like helical | Armadillo-type fold | Atypical Arm repeat | Importin-alpha, importin-beta-binding domain | Importin-alpha, importin-beta-binding domain superfamily | Importin subunit alpha |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q6DI01
|
525 |
Interactions and Pathways
No data available
Plasmids
No data available