Gene
otub1b
- ID
- ZDB-GENE-040718-204
- Name
- OTU deubiquitinase, ubiquitin aldehyde binding 1b
- Symbol
- otub1b Nomenclature History
- Previous Names
-
- otub1
- fa19h07
- wu:fa19h07 (1)
- zgc:92839
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to have NEDD8-specific protease activity; thiol-dependent ubiquitin-specific protease activity; and ubiquitin binding activity. Predicted to be involved in protein K48-linked deubiquitination. Predicted to localize to nucleus. Orthologous to human OTUB1 (OTU deubiquitinase, ubiquitin aldehyde binding 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6902223 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR003323 | OTU domain |
| Family | IPR016615 | Ubiquitin thioesterase Otubain |
| Family | IPR019400 | Peptidase C65, otubain |
| Homologous_superfamily | IPR038765 | Papain-like cysteine peptidase superfamily |
| Homologous_superfamily | IPR042467 | Peptidase C65, otubain, subdomain 2 |
| Homologous_superfamily | IPR042468 | Peptidase C65, otubain, subdomain 1 |
Domain Details Per Protein
| Protein | Length | OTU domain | Papain-like cysteine peptidase superfamily | Peptidase C65, otubain | Peptidase C65, otubain, subdomain 1 | Peptidase C65, otubain, subdomain 2 | Ubiquitin thioesterase Otubain |
|---|---|---|---|---|---|---|---|
|
UniProtKB:F6P1A9
|
266 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
otub1b-201
(1)
|
Ensembl | 1,196 nt | ||
| mRNA |
otub1b-202
(1)
|
Ensembl | 744 nt |
Interactions and Pathways
No data available
Plasmids
No data available