Gene

ldhbb

ID

ZDB-GENE-040718-176

Name

lactate dehydrogenase Bb

Symbol

ldhbb Nomenclature History

Previous Names

zgc:92882 (1)

Type

protein_coding_gene

Location

Chr: 25 Mapping Details/Browsers

Description

Predicted to enable L-lactate dehydrogenase activity. Predicted to act upstream of or within carbohydrate metabolic process and carboxylic acid metabolic process. Predicted to be located in cytoplasm. Is expressed in liver and retinal photoreceptor layer. Orthologous to human LDHB (lactate dehydrogenase B).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

9 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:92882 (5 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ldhbb Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		[Lactate dehydrogenase-B deficiency]	614128

Associated With ldhbb Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR018177	L-lactate dehydrogenase, active site
Domain	IPR001236	Lactate/malate dehydrogenase, N-terminal
Domain	IPR022383	Lactate/malate dehydrogenase, C-terminal
Family	IPR001557	L-lactate/malate dehydrogenase
Family	IPR011304	L-lactate dehydrogenase
Homologous_superfamily	IPR015955	Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
Homologous_superfamily	IPR036291	NAD(P)-binding domain superfamily

Domain Details Per Protein

Protein	Length	Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal	Lactate/malate dehydrogenase, C-terminal	Lactate/malate dehydrogenase, N-terminal	L-lactate dehydrogenase	L-lactate dehydrogenase, active site	L-lactate/malate dehydrogenase	NAD(P)-binding domain superfamily
UniProtKB:A0A8M2BIE4 InterPro	355
UniProtKB:Q6DGK2 InterPro	334
UniProtKB:B2GRW6 InterPro	334

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	ldhbb-201 (1) Ensembl	Ensembl	1,636 nt	Select Tool ZFIN BLAST
mRNA	ldhbb-202 (1) Ensembl	Ensembl	517 nt	Select Tool ZFIN BLAST
mRNA	ldhbb-203 (1) Ensembl	Ensembl	923 nt	Select Tool ZFIN BLAST
mRNA	ldhbb-205 (1) Ensembl	Ensembl	1,025 nt	Select Tool ZFIN BLAST
ncRNA	ldhbb-004 (1) Ensembl	Ensembl	561 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations