Gene
litaf
- ID
- ZDB-GENE-040704-23
- Name
- lipopolysaccharide-induced TNF factor
- Symbol
- litaf Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to have zinc ion binding activity. Predicted to localize to cytoplasmic side of endosome membrane; cytoplasmic side of lysosomal membrane; and cytoplasmic side of plasma membrane. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 1C. Is expressed in pronephric duct and pronephric duct opening. Orthologous to human LITAF (lipopolysaccharide induced TNF factor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:91882 (7 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Charcot-Marie-Tooth disease type 1C | Alliance | Charcot-Marie-Tooth disease, type 1C | 601098 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | LITAF domain containing protein | LPS-induced tumour necrosis factor alpha factor |
|---|---|---|---|
|
UniProtKB:A0A8M3AR44
|
162 | ||
|
UniProtKB:Q6GMG8
|
163 |
Interactions and Pathways
No data available
Plasmids
No data available