Gene
msrb3
- ID
- ZDB-GENE-040625-74
- Name
- methionine sulfoxide reductase B3
- Symbol
- msrb3 Nomenclature History
- Previous Names
-
- wu:fc07g04
- zgc:86909
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to have peptide-methionine (R)-S-oxide reductase activity. Involved in inner ear development. Predicted to localize to cytoplasm. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 74. Is expressed in heart rudiment; heart tube; inner ear; and myotome. Orthologous to human MSRB3 (methionine sulfoxide reductase B3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 10 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6905546 (6 images)
Wild Type Expression Summary
- All Phenotype Data
- 5 figures from Shen et al., 2015
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal recessive nonsyndromic deafness 74 | Alliance | Deafness, autosomal recessive 74 | 613718 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Mss4-like superfamily | Peptide methionine sulfoxide reductase MsrB | Peptide methionine sulphoxide reductase MrsB domain |
|---|---|---|---|---|
|
UniProtKB:A0A8M1P8M4
|
200 | |||
|
UniProtKB:Q5TZH8
|
187 | |||
|
UniProtKB:Q5TZH6
|
186 |
Interactions and Pathways
No data available
Plasmids
No data available