Gene
akr1b1.1
- ID
- ZDB-GENE-040625-7
- Name
- aldo-keto reductase family 1, member B1 (aldose reductase), tandem duplicate 1
- Symbol
- akr1b1.1 Nomenclature History
- Previous Names
-
- akr1b1
- zgc:86611 (1)
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to have alditol:NADP+ 1-oxidoreductase activity. Predicted to be involved in oxidation-reduction process. Predicted to localize to cytosol. Human ortholog(s) of this gene implicated in arteriosclerosis; cataract; diabetic neuropathy; diabetic retinopathy; and type 2 diabetes mellitus. Orthologous to human AKR1B1 (aldo-keto reductase family 1 member B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2005
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu329 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Dooley et al., 2019
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Aldo-keto reductase | Aldo/keto reductase, conserved site | NADP-dependent oxidoreductase domain | NADP-dependent oxidoreductase domain superfamily |
|---|---|---|---|---|---|
|
UniProtKB:Q6IQU1
|
315 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
akr1b1-201
(1)
|
Ensembl | 1,293 nt | ||
| mRNA |
akr1b1.1-202
(1)
|
Ensembl | 5,581 nt |
Interactions and Pathways
No data available
Plasmids
No data available