Gene

grem1a

ID
ZDB-GENE-040625-1
Name
gremlin 1a, DAN family BMP antagonist
Symbol
grem1a Nomenclature History
Previous Names
  • grem1
  • zgc:136702
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Predicted to have cytokine activity. Predicted to localize to extracellular space. Is expressed in several structures, including cranial vault; notochord; pectoral fin bud; pronephric duct; and segmental plate. Orthologous to human GREM1 (gremlin 1, DAN family BMP antagonist).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With grem1a Human Ortholog
No data available
Associated With grem1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR004133 DAN
Domain IPR006207 Cystine knot, C-terminal
Family IPR017159 Gremlin-1/2
Homologous_superfamily IPR029034 Cystine-knot cytokine
Domain Details Per Protein
Protein Length Cystine knot, C-terminal Cystine-knot cytokine DAN Gremlin-1/2
UniProtKB:Q6T937 177
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA grem1a-201 (1) Ensembl 1,297 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations