Gene
pth1a
- ID
- ZDB-GENE-040623-1
- Name
- parathyroid hormone 1a
- Symbol
- pth1a Nomenclature History
- Previous Names
-
- pth1 (1)
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Enables hormone activity. Acts upstream of or within calcium ion homeostasis and epidermal cell differentiation. Predicted to be located in extracellular region. Is expressed in several structures, including gill; heart; integument; nervous system; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in several diseases, including chronic kidney disease; diabetes mellitus (multiple); familial isolated hypoparathyroidism; hyperphosphatemia; and secondary hyperparathyroidism. Orthologous to human PTH (parathyroid hormone).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 12 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| familial isolated hypoparathyroidism | Alliance | Hypoparathyroidism, familial isolated 1 | 146200 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Parathyroid hormone | Parathyroid hormone/parathyroid hormone-related protein |
|---|---|---|---|
|
UniProtKB:Q6WQ25
|
102 |
Interactions and Pathways
No data available
Plasmids
No data available