Gene

zic4

ID

ZDB-GENE-040622-4

Name

zic family member 4

Symbol

zic4 Nomenclature History

Previous Names

fj36d02
wu:fj36d02
zgc:154123

Type

protein_coding_gene

Location

Chr: 24 Mapping Details/Browsers

Description

Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II regulatory region sequence-specific DNA binding activity. Involved in cell proliferation in hindbrain and fourth ventricle development. Predicted to localize to nucleus. Is expressed in several structures, including anterior neural keel; central nervous system; hindbrain neural rod; lateral plate mesoderm; and neural plate. Orthologous to human ZIC4 (Zic family member 4).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

10 figures from 4 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7143637 (11 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With zic4 Human Ortholog

No data available

Associated With zic4 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR013087	Zinc finger C2H2-type
Domain	IPR041643	ZIC protein, zinc finger domain
Family	IPR050329	GLI C2H2-type zinc-finger
Homologous_superfamily	IPR036236	Zinc finger C2H2 superfamily