Gene
serac1
- ID
- ZDB-GENE-040616-1
- Name
- serine active site containing 1
- Symbol
- serac1 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to be involved in phospholipid biosynthetic process. Predicted to localize to endoplasmic reticulum; integral component of membrane; and mitochondrion. Human ortholog(s) of this gene implicated in 3-methylglutaconic aciduria with deafness, encephalopathy, and Leigh-like syndrome. Orthologous to human SERAC1 (serine active site containing 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| 3-methylglutaconic aciduria with deafness, encephalopathy, and Leigh-like syndrome | Alliance | 3-methylglutaconic aciduria with deafness, encephalopathy, and Leigh-like syndrome | 614739 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Alpha/Beta hydrolase fold | Armadillo-like helical | Armadillo-type fold | SERAC1 |
|---|---|---|---|---|---|
|
UniProtKB:Q5SNQ7
|
|||||
|
UniProtKB:A0A8M9PSW7
|
658 | ||||
|
UniProtKB:A0A8M9PPI6
|
505 | ||||
|
UniProtKB:A0A8M1N7H8
|
586 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
serac1-201
(1)
|
Ensembl | 2,769 nt |
Interactions and Pathways
No data available
Plasmids
No data available