Gene

gdf11

ID
ZDB-GENE-040427-2
Name
growth differentiation factor 11
Symbol
gdf11 Nomenclature History
Previous Names
  • bmp11 (1)
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Predicted to have cytokine activity. Involved in anterior/posterior pattern specification. Predicted to localize to extracellular space. Is expressed in several structures, including brain; gonad; head; intermediate cell mass of mesoderm; and tail bud. Orthologous to human GDF11 (growth differentiation factor 11).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With gdf11 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
vertebral hypersegmentation and orofacial anomalies Alliance ?Vertebral hypersegmentation and orofacial anomalies 619122
Associated With gdf11 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017948 Transforming growth factor beta, conserved site
Domain IPR001111 TGF-beta, propeptide
Domain IPR001839 Transforming growth factor-beta, C-terminal
Family IPR015615 Transforming growth factor-beta-related
Homologous_superfamily IPR029034 Cystine-knot cytokine
Domain Details Per Protein
Protein Length Cystine-knot cytokine TGF-beta, propeptide Transforming growth factor beta, conserved site Transforming growth factor-beta, C-terminal Transforming growth factor-beta-related
UniProtKB:A0A8M2B1U5 389
UniProtKB:Q8JFP9 390
UniProtKB:A0A8M6Z378 229
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA gdf11-201 (1) Ensembl 1,727 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations