Gene

sardh

ID

ZDB-GENE-040426-996

Name

sarcosine dehydrogenase

Symbol

sardh Nomenclature History

Previous Names

zgc:56363 (1)

Type

protein_coding_gene

Location

Chr: 10 Mapping Details/Browsers

Description

Predicted to have sarcosine dehydrogenase activity. Predicted to be involved in sarcosine catabolic process. Predicted to localize to mitochondrial matrix. Is expressed in alar plate midbrain region; digestive system; myotome; nervous system; and yolk syncytial layer. Orthologous to human SARDH (sarcosine dehydrogenase).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

7 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:56363 (11 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With sardh Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
sarcosinemia	Alliance	[Sarcosinemia]	268900

Associated With sardh Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR006076	FAD dependent oxidoreductase
Domain	IPR006222	Aminomethyltransferase, folate-binding domain
Domain	IPR032503	FAD dependent oxidoreductase, central domain
Homologous_superfamily	IPR027266	GTP-binding protein TrmE/Aminomethyltransferase GcvT, domain 1
Homologous_superfamily	IPR029043	Glycine cleavage T-protein/YgfZ, C-terminal
Homologous_superfamily	IPR036188	FAD/NAD(P)-binding domain superfamily

Domain Details Per Protein

Protein	Length	Aminomethyltransferase, folate-binding domain	FAD dependent oxidoreductase	FAD dependent oxidoreductase, central domain	FAD/NAD(P)-binding domain superfamily	Glycine cleavage T-protein/YgfZ, C-terminal	GTP-binding protein TrmE/Aminomethyltransferase GcvT, domain 1
UniProtKB:F1Q5K3 InterPro	924

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	sardh-201 (1) Ensembl	Ensembl	3,023 nt	Select Tool
mRNA	sardh-202 (1) Ensembl	Ensembl	6,523 nt	Select Tool ZFIN BLAST
mRNA	sardh-203 (1) Ensembl	Ensembl	6,851 nt	Select Tool ZFIN BLAST
mRNA	sardh-204 (1) Ensembl	Ensembl	7,049 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations