Gene

pex5

ID
ZDB-GENE-040426-981
Name
peroxisomal biogenesis factor 5
Symbol
pex5 Nomenclature History
Previous Names
  • zgc:56318
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to have peroxisome matrix targeting signal-1 binding activity. Predicted to be involved in protein import into peroxisome matrix, docking. Predicted to localize to cytosol and peroxisomal membrane. Human ortholog(s) of this gene implicated in peroxisome biogenesis disorder 2A; peroxisome biogenesis disorder 2B; and rhizomelic chondrodysplasia punctata type 5. Orthologous to human PEX5 (peroxisomal biogenesis factor 5).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pex5 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
peroxisome biogenesis disorder 2A Alliance Peroxisome biogenesis disorder 2A (Zellweger) 214110
peroxisome biogenesis disorder 2B Alliance Peroxisome biogenesis disorder 2B 202370
rhizomelic chondrodysplasia punctata type 5 Alliance Rhizomelic chondrodysplasia punctata, type 5 616716
Associated With pex5 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR024111 PEX5/PEX5L
Homologous_superfamily IPR011990 Tetratricopeptide-like helical domain superfamily
Repeat IPR019734 Tetratricopeptide repeat
Domain Details Per Protein
Protein Length PEX5/PEX5L Tetratricopeptide-like helical domain superfamily Tetratricopeptide repeat
UniProtKB:Q7ZUZ1 600
UniProtKB:A0A8M3AHU4 645
UniProtKB:A0A8M3B1G9 416
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA pex5-201 (1) Ensembl 2,699 nt
mRNA pex5-202 (1) Ensembl 2,344 nt
mRNA pex5-203 (1) Ensembl 1,826 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations