Gene
atp5mc3a
- ID
- ZDB-GENE-040426-857
- Name
- ATP synthase membrane subunit c locus 3a
- Symbol
- atp5mc3a Nomenclature History
- Previous Names
-
- atp5g3
- atp5g3a
- zgc:55970
- zgc:86872
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to have proton-transporting ATP synthase activity, rotational mechanism. Predicted to be involved in ATP synthesis coupled proton transport. Predicted to localize to mitochondrial proton-transporting ATP synthase complex, coupling factor F(o). Human ortholog(s) of this gene implicated in renal cell carcinoma and urinary bladder cancer. Orthologous to several human genes including ATP5MC3 (ATP synthase membrane subunit c locus 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| early-onset dystonia and/or spastic paraplegia | Alliance | Dystonia, early-onset, and/or spastic paraplegia | 619681 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Binding_site | IPR020537 | ATP synthase, F0 complex, subunit C, DCCD-binding site |
| Domain | IPR002379 | V-ATPase proteolipid subunit C-like domain |
| Family | IPR000454 | ATP synthase, F0 complex, subunit C |
| Homologous_superfamily | IPR035921 | F/V-ATP synthase subunit C superfamily |
| Homologous_superfamily | IPR038662 | F1F0 ATP synthase subunit C superfamily |
Domain Details Per Protein
| Protein | Length | ATP synthase, F0 complex, subunit C | ATP synthase, F0 complex, subunit C, DCCD-binding site | F1F0 ATP synthase subunit C superfamily | F/V-ATP synthase subunit C superfamily | V-ATPase proteolipid subunit C-like domain |
|---|---|---|---|---|---|---|
|
UniProtKB:Q7ZYW7
|
139 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
atp5mc3a-201
(1)
|
Ensembl | 1,322 nt | ||
| mRNA |
atp5mc3a-202
(1)
|
Ensembl | 850 nt | ||
| ncRNA |
atp5g3a-003
(1)
|
Ensembl | 840 nt |
Interactions and Pathways
No data available
Plasmids
No data available