Gene
edem1
- ID
- ZDB-GENE-040426-808
- Name
- ER degradation enhancer, mannosidase alpha-like 1
- Symbol
- edem1 Nomenclature History
- Previous Names
-
- zgc:55816 (1)
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to enable calcium ion binding activity; hydrolase activity, hydrolyzing O-glycosyl compounds; and lytic transglycosylase activity. Predicted to be involved in endoplasmic reticulum mannose trimming and mannose trimming involved in glycoprotein ERAD pathway. Predicted to act upstream of or within carbohydrate metabolic process. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum. Is expressed in anterior axial hypoblast; hatching gland; liver; pharyngeal arch; and polster. Orthologous to human EDEM1 (ER degradation enhancing alpha-mannosidase like protein 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 19 figures from 14 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55816 (4 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | ER degradation-enhancing alpha-mannosidase-like protein 1/2/3 | Glycoside hydrolase family 47 | Seven-hairpin glycosidases | Six-hairpin glycosidase-like superfamily |
|---|---|---|---|---|---|
|
UniProtKB:E9QJF1
|
628 |
Interactions and Pathways
No data available
Plasmids
No data available