Gene

lin28ab

ID
ZDB-GENE-040426-747
Name
lin-28 homolog Ab
Symbol
lin28ab Nomenclature History
Previous Names
  • lin28
  • lin28a
  • sb:cb650
  • zgc:55584 (1)
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Predicted to have RNA binding activity and polysome binding activity. Involved in chordate embryonic development; negative regulation of gene expression; and regeneration. Predicted to localize to cytoplasmic ribonucleoprotein granule; nucleus; and polysome. Is expressed in several structures, including Kupffer's vesicle; central nervous system; digestive system; neural plate; and neural tube. Orthologous to human LIN28A (lin-28 homolog A).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
30 figures from 13 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With lin28ab Human Ortholog
No data available
Associated With lin28ab Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001878 Zinc finger, CCHC-type
Domain IPR002059 Cold-shock protein Csp, DNA-binding
Domain IPR011129 Cold-shock domain
Family IPR051373 Lin-28 homolog RNA-binding protein
Homologous_superfamily IPR012340 Nucleic acid-binding, OB-fold
Homologous_superfamily IPR036875 Zinc finger, CCHC-type superfamily
Domain Details Per Protein
Protein Length Cold-shock domain Cold-shock protein Csp, DNA-binding Lin-28 homolog RNA-binding protein Nucleic acid-binding, OB-fold Zinc finger, CCHC-type Zinc finger, CCHC-type superfamily
UniProtKB:Q803L0 202
UniProtKB:A0A2R8Q8W5 207
UniProtKB:I3IS11 194
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA lin28a-001 (1) Ensembl 2,020 nt
mRNA lin28a-203 (1) Ensembl 607 nt
mRNA lin28a-204 (1) Ensembl 547 nt
mRNA lin28a-206 (1) Ensembl 908 nt
mRNA lin28a-207 (1) Ensembl 6,269 nt
mRNA lin28a-208 (1) Ensembl 5,479 nt
mRNA lin28ab-202 (1) Ensembl 494 nt
ncRNA lin28a-005 (1) Ensembl 793 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations