Gene
tnpo3
- ID
- ZDB-GENE-040426-708
- Name
- transportin 3
- Symbol
- tnpo3 Nomenclature History
- Previous Names
-
- zgc:55409 (1)
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Involved in RNA splicing; T cell differentiation; and mRNA processing. Predicted to localize to cytoplasm. Human ortholog(s) of this gene implicated in autosomal dominant limb-girdle muscular dystrophy type 2. Orthologous to human TNPO3 (transportin 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55409 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal dominant limb-girdle muscular dystrophy type 2 | Alliance | Muscular dystrophy, limb-girdle, autosomal dominant 2 | 608423 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Armadillo-like helical | Armadillo-type fold | Exportin-1/Importin-beta-like | Importin beta-like nuclear transport receptors |
|---|---|---|---|---|---|
|
UniProtKB:Q7ZW13
|
923 |
Interactions and Pathways
No data available
Plasmids
No data available