Gene

zgc:55461

ID
ZDB-GENE-040426-2879
Name
zgc:55461
Symbol
zgc:55461 Nomenclature History
Previous Names
  • fd02b12 (1)
  • wu:fd02b12 (1)
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in microtubule cytoskeleton organization and mitotic cell cycle. Predicted to act upstream of or within microtubule-based process. Predicted to be located in cytoskeleton. Predicted to be active in cytoplasm and microtubule. Is expressed in several structures, including Kupffer's vesicle; axis; forerunner cell group; sensory system; and trigeminal placode. Human ortholog(s) of this gene implicated in Leber congenital amaurosis with early-onset deafness. Orthologous to human TUBB4B (tubulin beta 4B class IVb).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
17 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With zgc:55461 Human Ortholog
No data available
Associated With zgc:55461 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Binding_site IPR013838 Beta tubulin, autoregulation binding site
Conserved_site IPR017975 Tubulin, conserved site
Domain IPR003008 Tubulin/FtsZ, GTPase domain
Domain IPR018316 Tubulin/FtsZ, 2-layer sandwich domain
Family IPR000217 Tubulin
1 - 5 of 10 Show all
Domain Details Per Protein
Protein Length Beta tubulin Beta tubulin, autoregulation binding site Tubulin Tubulin, conserved site Tubulin, C-terminal Tubulin/FtsZ, 2-layer sandwich domain Tubulin/FtsZ, C-terminal Tubulin/FtsZ, GTPase domain Tubulin/FtsZ, GTPase domain superfamily Tubulin/FtsZ-like, C-terminal domain
UniProtKB:Q7ZW01 445
1 - 1 of 1
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA zgc:55461-001 (1) Ensembl 1,586 nt
1 - 1 of 1
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations