Gene
mapk4
- ID
- ZDB-GENE-040426-2835
- Name
- mitogen-activated protein kinase 4
- Symbol
- mapk4 Nomenclature History
- Previous Names
-
- ERK4 (1)
- wu:fi27d11
- zgc:55498
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction. Predicted to act upstream of or within protein phosphorylation. Predicted to be active in cytoplasm and nucleus. Is expressed in brain; digestive system; otic vesicle; post-vent region; and retina. Orthologous to human MAPK4 (mitogen-activated protein kinase 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from Krens et al., 2006
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Domain | IPR000719 | Protein kinase domain |
| Family | IPR008350 | Mitogen-activated protein (MAP) kinase, ERK3/4 |
| Family | IPR050117 | Mitogen-activated protein kinase |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Mitogen-activated protein kinase | Mitogen-activated protein (MAP) kinase, ERK3/4 | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site |
|---|---|---|---|---|---|---|---|
|
UniProtKB:B0V360
|
674 | ||||||
|
UniProtKB:Q803M9
|
674 |
Interactions and Pathways
No data available
Plasmids
No data available