Gene

ppm1na

ID

ZDB-GENE-040426-2731

Name

protein phosphatase, Mg2+/Mn2+ dependent, 1Na (putative)

Symbol

ppm1na Nomenclature History

Previous Names

zgc:73371

Type

protein_coding_gene

Location

Chr: 15 Mapping Details/Browsers

Description

Predicted to have magnesium-dependent protein serine/threonine phosphatase activity. Predicted to be involved in negative regulation of I-kappaB kinase/NF-kappaB signaling and positive regulation of canonical Wnt signaling pathway. Predicted to localize to cytosol and nucleus. Orthologous to human PPM1N (protein phosphatase, Mg2+/Mn2+ dependent 1N (putative)).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Chiang et al., 2019
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ppm1na Human Ortholog

No data available

Associated With ppm1na Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Binding_site	IPR000222	PPM-type phosphatase, divalent cation binding
Domain	IPR001932	PPM-type phosphatase-like domain
Domain	IPR012911	Protein serine/threonine phosphatase 2C, C-terminal
Family	IPR015655	Protein phosphatase 2C
Homologous_superfamily	IPR036457	PPM-type phosphatase-like domain superfamily
Homologous_superfamily	IPR036580	Phosphatase 2C, C-terminal domain superfamily