Gene
cdc45
- ID
- ZDB-GENE-040426-2710
- Name
- CDC45 cell division cycle 45 homolog (S. cerevisiae)
- Symbol
- cdc45 Nomenclature History
- Previous Names
-
- cdc45l
- wu:fi05h01
- zgc:56264 (1)
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to enable DNA replication origin binding activity; chromatin binding activity; and single-stranded DNA binding activity. Predicted to be involved in DNA replication initiation; double-strand break repair via break-induced replication; and mitotic DNA replication preinitiation complex assembly. Predicted to act upstream of or within DNA replication and cell division. Predicted to be located in nucleus. Predicted to be part of DNA replication preinitiation complex. Human ortholog(s) of this gene implicated in Meier-Gorlin syndrome 7. Orthologous to human CDC45 (cell division cycle 45).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:56264 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Meier-Gorlin syndrome 7 | Alliance | Meier-Gorlin syndrome 7 | 617063 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR003874 | CDC45 family |
Domain Details Per Protein
| Protein | Length | CDC45 family |
|---|---|---|
|
UniProtKB:Q7ZU79
|
572 |
Interactions and Pathways
No data available
Plasmids
No data available