Gene
timp2b
- ID
- ZDB-GENE-040426-2655
- Name
- TIMP metallopeptidase inhibitor 2b
- Symbol
- timp2b Nomenclature History
- Previous Names
-
- timp2l
- zgc:65967
- zgc:85799
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to have metalloendopeptidase inhibitor activity and protease binding activity. Predicted to be involved in negative regulation of proteolysis; response to cytokine; and response to hormone. Predicted to localize to extracellular matrix and extracellular space. Human ortholog(s) of this gene implicated in Moyamoya disease. Is expressed in caudal vein plexus and vasculature. Orthologous to human TIMP2 (TIMP metallopeptidase inhibitor 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 14 figures from 12 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:65967 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Charlton-Perkins et al., 2019
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Netrin domain | Protease inhibitor I35 (TIMP) | Proteinase inhibitor I35b (TIMP), C-terminal | Tissue inhibitor of metalloproteinases-like, OB-fold |
|---|---|---|---|---|---|
|
UniProtKB:Q6NUX9
|
217 |
Interactions and Pathways
No data available
Plasmids
No data available