Gene
lnx2b
- ID
- ZDB-GENE-040426-2500
- Name
- ligand of numb-protein X 2b
- Symbol
- lnx2b Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Exhibits ubiquitin-protein transferase activity. Involved in exocrine pancreas development and protein K48-linked ubiquitination. Is expressed in several structures, including blastodisc; mesoderm; nervous system; pronephros; and tail bud. Orthologous to human LNX2 (ligand of numb-protein X 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:85925 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Ro et al., 2009
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017907 | Zinc finger, RING-type, conserved site |
| Domain | IPR001478 | PDZ domain |
| Domain | IPR001841 | Zinc finger, RING-type |
| Domain | IPR018957 | Zinc finger, C3HC4 RING-type |
| Family | IPR051342 | PDZ domain-containing scaffold protein |
| Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
| Homologous_superfamily | IPR036034 | PDZ superfamily |
Domain Details Per Protein
| Protein | Length | PDZ domain | PDZ domain-containing scaffold protein | PDZ superfamily | Zinc finger, C3HC4 RING-type | Zinc finger, RING/FYVE/PHD-type | Zinc finger, RING-type | Zinc finger, RING-type, conserved site |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A4VCF7
|
678 |
Interactions and Pathways
No data available
Plasmids