Gene

pccb

ID

ZDB-GENE-040426-2467

Name

propionyl-CoA carboxylase subunit beta

Symbol

pccb Nomenclature History

Previous Names

zgc:85813

Type

protein_coding_gene

Location

Chr: 2 Mapping Details/Browsers

Description

Predicted to have ligase activity. Human ortholog(s) of this gene implicated in amino acid metabolic disorder and propionic acidemia. Is expressed in several structures, including alar plate midbrain region; musculature system; optic tectum; optic vesicle; and pronephros. Orthologous to human PCCB (propionyl-CoA carboxylase subunit beta).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

8 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:6893522 (1 image)
IMAGE:7148931 (5 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With pccb Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
propionic acidemia	Alliance	Propionicacidemia	606054

Associated With pccb Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR011762	Acetyl-coenzyme A carboxyltransferase, N-terminal
Domain	IPR011763	Acetyl-coenzyme A carboxyltransferase, C-terminal
Domain	IPR034733	Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta
Family	IPR051047	Acyl-CoA Carboxylase Beta Subunit
Homologous_superfamily	IPR029045	ClpP/crotonase-like domain superfamily