Gene
map3k12
- ID
- ZDB-GENE-040426-2436
- Name
- mitogen-activated protein kinase kinase kinase 12
- Symbol
- map3k12 Nomenclature History
- Previous Names
-
- zgc:77370
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to have JUN kinase kinase kinase activity. Predicted to be involved in activation of JUN kinase activity. Is expressed in central nervous system; cranial ganglion; neural tube; neurons; and retina. Orthologous to human MAP3K12 (mitogen-activated protein kinase kinase kinase 12).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:77370 (9 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Adula et al., 2022
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR001245 | Serine-threonine/tyrosine-protein kinase, catalytic domain |
| Family | IPR017419 | Mitogen-activated protein kinase kinase kinase 12/13 |
| Family | IPR027257 | Mitogen-activated protein kinase kinase kinase 12 |
| Family | IPR050167 | Serine/threonine-protein kinase |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Mitogen-activated protein kinase kinase kinase 12 | Mitogen-activated protein kinase kinase kinase 12/13 | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase | Serine/threonine-protein kinase, active site | Serine-threonine/tyrosine-protein kinase, catalytic domain |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q6NYW1
|
856 | |||||||
|
UniProtKB:A0A8M2BER7
|
897 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA | map3k12-001 (1) | 3,666 nt | |||
| mRNA |
map3k12-201
(1)
|
Ensembl | 3,532 nt |
Interactions and Pathways
No data available
Plasmids
No data available