Gene

wrnip1

ID
ZDB-GENE-040426-2415
Name
WRN helicase interacting protein 1
Symbol
wrnip1 Nomenclature History
Previous Names
  • zgc:85976 (1)
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to have enzyme activator activity and single-stranded DNA helicase activity. Predicted to be involved in DNA-dependent DNA replication and regulation of DNA repair. Predicted to localize to nucleus. Orthologous to human WRNIP1 (WRN helicase interacting protein 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Babu et al., 2022
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With wrnip1 Human Ortholog
No data available
Associated With wrnip1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003593 AAA+ ATPase domain
Domain IPR003959 ATPase, AAA-type, core
Domain IPR006642 Rad18, zinc finger UBZ4-type
Domain IPR021886 MgsA AAA+ ATPase C-terminal
Domain IPR032423 AAA C-terminal domain
Family IPR051314 AAA ATPase RarA/MGS1/WRNIP1
Homologous_superfamily IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Domain Details Per Protein
Protein Length AAA+ ATPase domain AAA ATPase RarA/MGS1/WRNIP1 AAA C-terminal domain ATPase, AAA-type, core DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal MgsA AAA+ ATPase C-terminal P-loop containing nucleoside triphosphate hydrolase Rad18, zinc finger UBZ4-type
UniProtKB:Q6NW46 546
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA wrnip1-201 (1) Ensembl 2,302 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations