Gene

csnk1db

ID

ZDB-GENE-040426-2385

Name

casein kinase 1, delta b

Symbol

csnk1db Nomenclature History

Previous Names

csnk1d
wu:fb69b03
wu:fj97a05
zgc:77627

Type

protein_coding_gene

Location

Chr: 12 Mapping Details/Browsers

Description

Predicted to have protein serine/threonine kinase activity. Predicted to be involved in several processes, including non-motile cilium assembly; positive regulation of canonical Wnt signaling pathway; and positive regulation of proteasomal ubiquitin-dependent protein catabolic process. Predicted to localize to cytoplasm; nucleus; and spindle microtubule. Human ortholog(s) of this gene implicated in advanced sleep phase syndrome 2. Is expressed in several structures, including axis; brain; notochord; presumptive neural retina; and yolk syncytial layer. Orthologous to human CSNK1D (casein kinase 1 delta).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

9 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:77627 (6 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With csnk1db Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
advanced sleep phase syndrome 2	Alliance	Advanced sleep-phase syndrome, familial, 2	615224

Associated With csnk1db Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR008271	Serine/threonine-protein kinase, active site
Binding_site	IPR017441	Protein kinase, ATP binding site
Domain	IPR000719	Protein kinase domain
Family	IPR050235	Casein Kinase 1 Ser/Thr Protein Kinase
Homologous_superfamily	IPR011009	Protein kinase-like domain superfamily