Gene

acot17

ID

ZDB-GENE-040426-2381

Name

acyl-CoA thioesterase 17

Symbol

acot17 Nomenclature History

Previous Names

wu:fc48e10
zgc:77651

Type

protein_coding_gene

Location

Chr: 4 Mapping Details/Browsers

Description

Predicted to have acyl-CoA hydrolase activity. Predicted to be involved in acyl-CoA metabolic process and fatty acid metabolic process. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in disease of metabolism. Is expressed in liver and yolk syncytial layer. Orthologous to several human genes including ACOT1 (acyl-CoA thioesterase 1); ACOT2 (acyl-CoA thioesterase 2); and ACOT4 (acyl-CoA thioesterase 4).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

7 figures from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:77651 (4 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With acot17 Human Ortholog

No data available

Associated With acot17 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR006862	Acyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase
Domain	IPR014940	BAAT/Acyl-CoA thioester hydrolase C-terminal
Family	IPR016662	Acyl-CoA thioesterase, long chain
Homologous_superfamily	IPR029058	Alpha/Beta hydrolase fold
Homologous_superfamily	IPR042490	Acyl-CoA thioester hydrolase/BAAT, N-terminal