Gene
slc22a2
- ID
- ZDB-GENE-040426-2167
- Name
- solute carrier family 22 member 2
- Symbol
- slc22a2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Exhibits transmembrane transporter activity. Predicted to be involved in organic cation transport. Localizes to integral component of plasma membrane. Human ortholog(s) of this gene implicated in acute kidney failure. Is expressed in several structures, including eye; heart; liver; pleuroperitoneal region; and skeletal muscle. Orthologous to several human genes including SLC22A2 (solute carrier family 22 member 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:64076 (2 images)
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Shim et al., 2019
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR005829 | Sugar transporter, conserved site |
| Domain | IPR020846 | Major facilitator superfamily domain |
| Family | IPR004749 | Organic cation transport protein/SVOP |
| Family | IPR005828 | Major facilitator, sugar transporter-like |
| Homologous_superfamily | IPR036259 | MFS transporter superfamily |
Domain Details Per Protein
| Protein | Length | Major facilitator, sugar transporter-like | Major facilitator superfamily domain | MFS transporter superfamily | Organic cation transport protein/SVOP | Sugar transporter, conserved site |
|---|---|---|---|---|---|---|
|
UniProtKB:Q7T2C0
|
562 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
slc22a2-201
(1)
|
Ensembl | 2,849 nt |
Interactions and Pathways
No data available
Plasmids
No data available