Gene
rhoaa
- ID
- ZDB-GENE-040426-2150
- Name
- ras homolog gene family, member Aa
- Symbol
- rhoaa Nomenclature History
- Previous Names
-
- wu:fa66g04
- wu:fb26g07
- zgc:66058
- zgc:85805 (1)
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to have GTP binding activity; GTPase activity; and protein kinase binding activity. Predicted to be involved in several processes, including actin cytoskeleton organization; skeletal muscle satellite cell migration; and wound healing, spreading of cells. Predicted to localize to several cellular components, including cell cortex; cell division site; and cytoplasmic vesicle. Human ortholog(s) of this gene implicated in breast carcinoma. Orthologous to human RHOA (ras homolog family member A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Salas-Vidal et al., 2005
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Ectodermal dysplasia with facial dysmorphism and acral, ocular, and brain anomalies, somatic mosaic | 618727 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | P-loop containing nucleoside triphosphate hydrolase | Small GTPase | Small GTPase Rho | Small GTP-binding domain |
|---|---|---|---|---|---|
|
UniProtKB:Q6NUX8
|
193 |
Interactions and Pathways
No data available
Plasmids