Gene
cyb5a
- ID
- ZDB-GENE-040426-2148
- Name
- cytochrome b5 type A (microsomal)
- Symbol
- cyb5a Nomenclature History
- Previous Names
-
- wu:fb44a11
- zgc:64123
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Exhibits heme binding activity. Involved in cellular response to xenobiotic stimulus and oxidation-reduction process. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in methemoglobinemia. Is expressed in digestive system; head; immature eye; neural crest; and optic stalk. Orthologous to human CYB5A (cytochrome b5 type A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:64123 (7 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| methemoglobinemia and ambiguous genitalia | Alliance | Methemoglobinemia and ambiguous genitalia | 250790 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cytochrome b5 | Cytochrome b5, heme-binding site | Cytochrome b5-like heme/steroid binding domain | Cytochrome b5-like heme/steroid binding domain superfamily |
|---|---|---|---|---|---|
|
UniProtKB:A8WGS0
|
137 | ||||
|
UniProtKB:Q7T341
|
137 |
Interactions and Pathways
No data available
Plasmids
No data available