Gene
ddost
- ID
- ZDB-GENE-040426-2147
- Name
- dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)
- Symbol
- ddost Nomenclature History
- Previous Names
-
- wu:fa11d01
- zgc:66068
- zgc:77478
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to contribute to dolichyl-diphosphooligosaccharide-protein glycotransferase activity. Predicted to be involved in protein N-linked glycosylation via asparagine. Predicted to localize to oligosaccharyltransferase complex. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Ir. Is expressed in axis; notochord; and polster. Orthologous to human DDOST (dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6905658 (9 images)
- IMAGE:7161736 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| congenital disorder of glycosylation Ir | Alliance | Congenital disorder of glycosylation, type Ir | 614507 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR005013 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48kDa subunit |
Domain Details Per Protein
| Protein | Length | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48kDa subunit |
|---|---|---|
|
UniProtKB:Q6NYS8
|
441 | |
|
UniProtKB:A0A0R4I9F5
|
441 |
Interactions and Pathways
No data available
Plasmids
No data available